Britons have been warned to expect congested roads, busy airports and disruption to trains as they head into the bank holiday weekend.
Up to 11 million people will take to the roads this weekend, the RAC said, with traffic expected to build up on major roads later on Friday.
Railway passengers face difficulties, with some having to travel on buses instead of trains, as Network Rail undertakes extensive engineering work.
According to the rail watchdog Passenger Focus, customers would rather have a longer train journey than have to ride on a bus.
Only four Tube lines on the London Underground will run normal services this weekend, with Victoria and Waterloo & City shutting completely, while there will be part closures on five other lines.
The RAC added that the heaviest traffic is likely to affect southern and central England.
The M4, M5 and A303 into the West Country and Wales, the M6 and A590 to the Lake District and the M55 to Blackpool are expected to be the busiest areas over the weekend.
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