David Cameron is being urged to cut the cost of fuel duty by 3p a litre ahead of the Budget next week.
Motoring campaign group FairFuelUK called on the Prime Minister to slash the rate of tax on petrol in a letter delivered to Number 10 on Tuesday.
The plea has been backed by the RAC and the Freight Transport Association as well as 100 MPs and "500,000 supporters and the 32 million road users".
"Your clear awareness of the debilitating effects of rising transport costs in a road economy is to be warmly congratulated," says the letter addressed to Mr Cameron.
"But FairFuelUK and the 100 MPs who have been such staunch supporters since 2011 believe there's more to be done.
"We are calling on you to support a 3p duty cut that will continue to bolster the economic recovery. And that recovery so far has been bankrolled by consumer spending and not by industry or manufacturing."
RAC spokesman Simon Williams said: "With so many people struggling day-to-day to make ends meet and being forced to cut back on the essential use of their motor vehicle, the Government should be looking to help drivers by cutting fuel duty.
"Independent research by the National Institute for Social and Economic Research and the Centre for Economic and Business Research has clearly demonstrated the link between fuel prices, unemployment and economic shrinkage.
"There has never been a more expensive time to be a motorist and the RAC, alongside other supporters of the FairFuelUK campaign, will continue to lobby the Government to raise awareness of the hardship faced by the UK's motorists and ultimately drive down costs at the pumps.
"Rising fuel prices cause economic hardship for millions and hinder the growth of the economy, and for the tens of millions of households who rely on their car, this news could not have come at a worse time."
A recent ComRes Poll found that 69% of UK adults would like to see the Government reduce the level of fuel duty in the next budget by at least 1p.
The poll also revealed that 59% would like a reduction of 3p and 31% wanted 10p knocked off the cost.
FairFuelUK said that 67% of the population use their cars for "essential" food shopping and 50% drive to work.
Copyright Press Association 2014