Winds of up to 90mph are due to hit Northern Ireland and parts of western Scotland, while flood warnings for immediate action have been put in place around the UK - including 26 in the South West of England.
The warning from the Met Office specifies that large waves threaten coastal areas, while Scotland can also expect 20cm of snow. Drivers in many areas of England must watch out for icy roads, with rail passengers also warned that they could face delays.
RAC patrol ambassador Baldi Singh said: "Scotland and the North of England are facing the brunt of this weather front.
"We have increased the number of patrols on the roads by 10% to help members facing breakdowns and minor accidents arising from the very damp and icy conditions. Battery faults are the biggest cause of call-outs and are causing some real headaches for motorists as the icy weather is playing havoc with electrics and early cold starts.
"I would advise drivers to take extra care on the roads, reduce your speed, avoid accelerating or braking sharply and leave plenty of space between your car and the vehicle in front on icy or snowy roads as it can take 10 times the normal distance to stop.
"If you encounter a skid then steer into it to regain control and then steer back on course - don't take your hands off the wheel or stamp your foot on the brakes."
Somerset and Devon could see flooding rivers this week, with likely ones including Yeo, Tamar, Brue, Torridge, Teign and Axe.
Another 116 flood alerts have been put in place, with Wales and the Midlands accounting for many of these.
Cumbria earlier saw the closure of the A595 at Moota when a hotel had its roof blown off, while an overturned lorry saw the M6 partially shut southbound between junctions 38 and 37.
Copyright Press Association 2013