According to plans released by Highways England, the scheme will see the A19 lowered beneath the existing A1058 Coast Road and roundabout.
Due to begin next month, the project will allow drivers travelling on the A19 to go straight on without the need to queue at the roundabout.
The road is part of the main route to and from the Tyne Tunnel and is used by thousands of drivers every day.
In a statement, Highways England project manager Julie Alexander said that the aim of the work was to speed up journey times and help to reduce traffic volumes.
“Once complete, this scheme will improve journey times on the A19 by reducing congestion and improving safety for the thousands of drivers that use this junction each day, as well as cyclists and pedestrians,” she said.
“The A19 is a vital strategic link providing access to the Tyne Tunnel Trading Estate, Silverlink Retail Park, Cobalt Business Park and South East Northumberland.”
When work gets under way on the project, the speed limit on the A19 and slip roads will be lowered to 30mph, with narrow lanes also in place.
The speed limit on the A1058 Coast Road will also be lowered to 30mph.
In addition, project organisers expect that overnight carriageway closures will be necessary, though these will be advertised closer to the time.
The improvements are being financed from the Government’s £15 billion roads investment strategy, which it is hoped will speed up connections between major cities over the next five years.
As part of this strategy, a £61m extension to the A1 near Gateshead has also been completed, running from Coal House to Metro Centre.
This is expected to increase capacity for drivers, who are now able to use an extra lane in each direction, as well as two new local link roads.
In total, eight miles of extra lanes were added to the A1, benefitting the 116,000 drivers who use the road every day.